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KMID : 1001920080440040273
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Journal of Korean Neurosurgical Society
2008 Volume.44 No. 4 p.273 ~ p.276
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Skull Base Invasion of Adenoid Cystic Carcinoma of the Lacrimal Gland : A Case Report
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Lee Jae-Il
Kim Young-Zoon
Lee Eun-Hee
Kim Kyu-Hong
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Abstract
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Although adenoid cystic carcinoma (ACC) of the lacrimal gland is a rarely encountered orbital tumor, it invades intracranially more frequently than carcinomas of other glands in the head and neck. A 52-year-old man underwent orbital exenteration and resection of intracranially extended tumor via a fronto-orbito-zygomatic approach in combination with a transfacial approach. Histopathologically, the tumor showed perineural, vascular, and lymphatic invasion. Additionally, he received radiotherapy (60 Gy) and adjuvant systemic cisplatin and 5-fluorouracil chemotherapy due to residual tumor in the orbit and systemic metastases (lung, ribs, and spines). He was free of progression and recurrence at 6 months after treatment. The authors report a case of skull base invasion by an ACC of the lacrimal gland to remind neurosurgeons planning intervention that this disease shows a tendency to invade intracranially.
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KEYWORD
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Adenoid cystic carcinoma, Skull base, Metastasis, Prognosis
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